Original Australian Daybill Movie Poster.The Island of Dr. Moreau is a 1996 American science fiction horror film, the third major film adaptation of H. G. Wells' novel The Island of Doctor Moreau, about a scientist who attempts to convert animals into people. The film stars Marlon Brando, David Thewlis, Val Kilmer, Ron Perlman, and Fairuza Balk, and was directed by John Frankenheimer. The film got nominations for two Saturn Awards: Best Make-Up and Science Fiction Film.